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As with many psychedelic substances, the effects of psychedelic mushrooms are subjective and can vary considerably among individual users.The mind-altering effects of psilocybin-containing mushrooms typically last from three to eight hours depending on dosage, preparation method, and personal metabolism.

The doctor who treated them later described how the youngest child "was attacked with fits of immoderate laughter, nor could the threats of his father or mother refrain him." In 1955, Valentina and R.The first 3–4 hours of the trip are typically referred to as the 'peak' in which the user experiences more vivid visuals, and distortions in reality.However, the effects can seem to last much longer to the user because of psilocybin's ability to alter time perception.Gordon Wasson became the first known Caucasians to actively participate in an indigenous mushroom ceremony.The Wassons did much to publicize their discovery, even publishing an article on their experiences in Life in 1957.Over 100 species are classified in the genus Psilocybe.Psilocybin mushrooms may have been used since prehistoric times.Mushroom stones and motifs have been found in Guatemala. A Psilocybe species was known to the Aztecs as teōnanācatl (literally "divine mushroom" - agglutinative form of teōtl (god, sacred) and nanācatl (mushroom) in Náhuatl) and were reportedly served at the coronation of the Aztec ruler Moctezuma II in 1502.Aztecs and Mazatecs referred to psilocybin mushrooms as genius mushrooms, divinatory mushrooms, and wondrous mushrooms, when translated into English.The availability of psilocybin mushrooms from wild and cultivated sources has made it among the most widely used of the psychedelic drugs.At present, psilocybin mushroom use has been reported among some groups spanning from central Mexico to Oaxaca, including groups of Nahua, Mixtecs, Mixe, Mazatecs, Zapotecs, and others.

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